Cajun Chicken Cream Pasta

Featured in: Cozy Weeknight Dinners

This dish combines succulent chicken strips seasoned with bold Cajun spices, sautéed bell peppers, and a smooth, garlicky cream sauce. Cooked pasta is tossed into the sauce and chicken, creating a harmonious blend of flavors and textures. The dish is garnished with fresh parsley and Parmesan, making it an ideal choice for a flavorful weeknight dinner that’s both satisfying and easy to prepare.

Updated on Wed, 24 Dec 2025 12:11:00 GMT
Creamy Cajun Chicken Pasta with colorful bell peppers and parmesan cheese served hot. Save to Pinterest
Creamy Cajun Chicken Pasta with colorful bell peppers and parmesan cheese served hot. | messlitreats.com

There's something about the smell of Cajun spices hitting hot oil that makes you feel like you're cooking something important. I discovered this pasta on a Tuesday night when I had chicken, cream, and barely any plan—just the confidence that bold flavors could save a simple weeknight. Twenty-five minutes later, my kitchen smelled like New Orleans, and suddenly everyone at the table was asking for seconds.

I made this for a friend who said she couldn't handle spicy food, and she ended up eating three helpings. That's when I realized Cajun seasoning isn't about heat—it's about depth, warmth, and that savory complexity that makes people say yes to another bite before they even realize what's happened.

Ingredients

  • Chicken breasts: Slicing them into strips instead of cooking them whole means they cook through quickly and absorb the seasoning better.
  • Cajun seasoning: This is your backbone—check that it's fresh and hasn't been sitting in the back of your cabinet for two years, or it'll taste flat.
  • Penne or fettuccine: Either works, but thinner pasta gets coated more evenly by the cream sauce.
  • Bell peppers: The red and yellow ones add sweetness that balances the spice beautifully.
  • Heavy cream: Don't skimp here—this is what makes the sauce silky and rich.
  • Parmesan cheese: Freshly grated melts into the sauce like silk, while pre-shredded cheese can get grainy.
  • Garlic: Mince it fine so it dissolves into the sauce rather than leaving harsh chunks.
  • Butter: This is where the vegetables start to caramelize slightly, building flavor before the cream goes in.

Instructions

Start the pasta:
Get a pot of salted water boiling while you prep everything else. This becomes your safety net—if anything cooks faster than expected, you've already got pasta nearly ready.
Season the chicken:
Coat those strips generously and let them sit for a minute so the seasoning sticks instead of sliding off into the pan.
Sear the chicken:
Get your skillet hot, oil shimmering, then slide in the chicken. Listen for that sizzle—it means you're doing it right. Let it brown without moving it around constantly, about 5-7 minutes total.
Soften the vegetables:
In the same unwashed pan, melt butter and let those peppers, onion, and garlic get soft and slightly golden. This takes about 4-5 minutes, and the pan's brown bits are liquid gold for flavor.
Build the sauce:
Pour in cream and broth, scraping the bottom of the pan with your wooden spoon. Let it bubble gently for 2-3 minutes until it thickens slightly—you're looking for something that coats the back of a spoon.
Melt in the cheese:
Lower the heat, add Parmesan, and stir until it disappears into the sauce. Taste it now and adjust salt and pepper—the pasta water will be salty, so be conservative.
Bring it together:
Add the cooked pasta, chicken, and a splash of that reserved pasta water you saved. Toss everything until it's evenly coated and heated through, about 1-2 minutes.
Finish and serve:
Plate immediately while it's steaming, top with parsley and extra Parmesan, and watch people's faces light up.
Delicious Cajun Chicken Pasta, perfectly plated, ready to enjoy with fresh parsley as a garnish. Save to Pinterest
Delicious Cajun Chicken Pasta, perfectly plated, ready to enjoy with fresh parsley as a garnish. | messlitreats.com

The first time someone told me this pasta reminded them of a restaurant they loved, I felt something click into place. Food that's this easy to make but feels this special creates a kind of quiet magic in a kitchen.

Timing and Prep

Mise en place saves you here—chop and measure everything before you start cooking. Once the chicken hits the pan, you're moving fast, and scrambling for ingredients while something's burning is how weeknight dinners become stressful instead of satisfying. I usually set out all my spices, cream, cheese, and broth in small bowls so I can grab them without thinking.

Variations That Work

Shrimp swaps in beautifully—use the same amount, but reduce the cooking time to 2-3 minutes since they cook faster than chicken. Mushrooms add earthiness if you want to stretch the dish or make it feel heavier. Some nights I add a handful of spinach right at the end, just enough to wilt into the sauce without making it feel like health food.

Why This Tastes Like Home

Cajun seasoning has this way of making simple ingredients feel bold and intentional, like you knew exactly what you were doing from the start. The cream mellows the spice just enough that it feels comforting instead of challenging, and the vegetables hidden throughout give you little pockets of sweetness that surprise you between bites.

  • Add a pinch of cayenne if you want more heat, or use mild seasoning if your family prefers gentle flavors.
  • Don't skip the parsley garnish—it brightens everything and gives the dish color.
  • Leftover cream sauce freezes beautifully, so doubling this recipe is always smart.
A close-up view of flavorful Cajun Chicken Pasta, with a rich, creamy sauce and tender chicken. Save to Pinterest
A close-up view of flavorful Cajun Chicken Pasta, with a rich, creamy sauce and tender chicken. | messlitreats.com

This is the kind of dinner that proves you don't need complicated recipes or hours at the stove to feed people something they'll remember. Make it once, and you'll find yourself coming back to it on nights when you need something that feels both comforting and a little bit special.

Common Recipe Questions

What type of pasta works best with this dish?

Penne or fettuccine are recommended as they hold the creamy sauce well and complement the texture of the chicken and peppers.

Can I adjust the spice level?

Yes, adding a pinch of cayenne or choosing a spicier Cajun seasoning can increase the heat to your preference.

Is it possible to substitute the chicken?

Shrimp can be used instead of chicken for a seafood variation, offering a different but equally delicious flavor profile.

How can I make this dish gluten-free?

Simply replace the regular pasta with gluten-free pasta to accommodate dietary restrictions without sacrificing taste.

What can be served as a garnish?

Fresh parsley and extra grated Parmesan cheese enhance both the flavor and presentation of the dish.

Cajun Chicken Cream Pasta

Tender Cajun-spiced chicken and peppers in a creamy sauce tossed with pasta for a comforting meal.

Prep Duration
15 min
Cooking Duration
25 min
Overall Duration
40 min
Created by messli Sophie Lane


Skill Required Medium

Cuisine Origin American (Cajun-inspired)

Portion Yield 4 People served

Diet Preferences None specified

List of Ingredients

Chicken

01 2 large boneless, skinless chicken breasts, sliced into strips (approx. 1 lb)
02 1 ½ tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 oz penne or fettuccine pasta

Vegetables

01 1 red bell pepper, thinly sliced
02 1 yellow bell pepper, thinly sliced
03 1 small red onion, thinly sliced
04 2 cloves garlic, minced

Sauce

01 2 tablespoons unsalted butter
02 1 cup heavy cream
03 ¼ cup chicken broth
04 ½ cup freshly grated Parmesan cheese
05 Salt and black pepper, to taste

Garnish

01 Fresh parsley, chopped
02 Extra Parmesan cheese

Step-by-Step Directions

Step 01

Cook Pasta: Boil salted water in a large pot and cook pasta until al dente. Drain, reserving ¼ cup of pasta water, then set aside.

Step 02

Season Chicken: Toss chicken strips with Cajun seasoning to coat evenly.

Step 03

Sauté Chicken: Heat olive oil in a large skillet over medium-high heat. Add chicken and sauté for 5–7 minutes until browned and cooked through. Remove and set aside.

Step 04

Cook Vegetables: In the same skillet, melt butter over medium heat. Add bell peppers, red onion, and garlic. Sauté for 4–5 minutes until softened.

Step 05

Prepare Sauce: Pour in heavy cream and chicken broth, stirring well and scraping browned bits from the pan. Simmer for 2–3 minutes until slightly thickened.

Step 06

Finish Sauce: Reduce heat to low. Stir in Parmesan until melted and sauce is creamy. Season with salt and black pepper to taste.

Step 07

Combine Pasta and Chicken: Add cooked pasta, sautéed chicken, and reserved pasta water to the skillet. Toss to coat evenly and heat through.

Step 08

Serve: Plate immediately, garnishing with fresh parsley and extra Parmesan cheese.

Kitchen Tools Needed

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Colander

Allergy Warnings

Check all listed ingredients for allergens. Reach out to a healthcare provider if you aren't sure.
  • Contains dairy (cream, butter, Parmesan)
  • Contains wheat (pasta)
  • May contain sulfites in Cajun seasoning

Nutrition per serving

Nutritional details are just for your reference. Always talk to a doctor for specific health advice.
  • Energy (Calories): 610
  • Fats: 26 g
  • Carbohydrates: 56 g
  • Proteins: 36 g